Salford, beaten finalists in 2009-10, have a first round fixture at home to County League opposition in Lytham St.Annes.
Premier League newcomers Rochdale will host Padiham in the 2nd Round, Curzon Ashton entertain the winners of the Sefton Peronni versus Lancaster City tie, Dalton have a big home game with Preston North End, while there's a Blackpool derby at Wren Rovers.
Lancashire Cup 1st Round Draw: (September 19th 2010)
Salford v Lytham St.Annes
Penwortham v Leyland
Sefton Peronni v Lancaster City
2nd Round: (October 17th)
Morecambe v Salford or Lytham St.Annes
Bolton Wanderers v Blackburn Rovers
Accrington Girls & Ladies v Penwortham or Leyland
Rochdale v Padiham
Blackpool Wren Rovers v Blackpool FC Ladies
Curzon Ashton v Sefton Peronni or Lancaster City
Dalton v Preston North End
Wythenshawe Amateurs v Springfields (Preston)
